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All authors participated in critical review of the manuscript

Conversely, NEDD4 binding protein 3 (N4BP3) exacerbates the inflammatory response by facilitating K63-linked ubiquitination of RIPK2, suggesting that regulating RIPK2 ubiquitination status may also serve as a potential therapeutic target [466,467,468]

Woreta, Johns Hopkins Medicine, Baltimore, MD and Saleh A Alqahtani, Johns Hopkins University School of Medicine

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Increases glucose uptake in muscle tissue and enhances insulin sensitivity, supporting improved nutrient partitioning and metabolic health markers