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C.PetrilloS.BottinoF.et al (2022)

The infusion begins slowly, and if no reactions occur, it continues for 45-60 minutes

Key Takeaways Weeks 1-4: Sleep quality improves first

A single contamination event or potency error can render therapy ineffective or worse, dangerous

Strong clinical documentation is critical and should include: Mechanism of injury (e.g., whiplash, fall) Physical exam findings (tenderness, spasm, ROM limitation) Symptom correlation and treatment plan Clear linkage between diagnosis and management supports medical necessity and audit compliance

Dysregulation of heme metabolism In the mitochondria, iron can also be complexed to a porphyrin ring to generate heme