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Tumor xenografts in nude mice Single-cell suspensions (5 10 6 cells) of SW48 isogenic cells were subcutaneously injected into the left flank of 5-week-old athymic nude mice (Koatech, Korea)

The results, which were published in the journal Diabetes Care , found that supplementation restored GSH levels and lowered oxidative damage caused by high glucose numbers

By inhibiting lipid ROS generation and the hyperpolarization of mitochondrial membrane potential, mitoglitazone could restore mitochondrial DNA copy number, the generation of ATP, and mitochondrial morphology in kidney tissue, inhibiting mitochondrial dysfunction and ferroptosis induced by I/R

Oxidation of a cytosolic molecule, promoting formation of the disulfide-bonded form, will only occur under conditions of oxidative stress

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