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Researchers might explore this combination in models of severe metabolic dysfunction where both NAD+ depletion and poor mitochondrial health are present

Diet Vitamin B12 can only be found in animal foods, so vegans and vegetarians are particularly at risk (studies show that 50% of long term vegetarians, and 80% of vegans could be deficient) Alcohol and medications such as PPIs, acid suppressors, and Metformin are also risks for deficiency Poor digestion, including

The answer depends on the treatment goal, delivery method, comfort level, medical history, and provider guidance

Buers, et al

Methylcobalamin is the easiest form of Vitamin B12 for the body to absorb

Forward-looking statements are based on Cigna's current expectations and projections about future trends, events and uncertainties