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Vitamin C induces human melanoma A375 cell apoptosis via Bax- and Bcl-2-mediated mitochondrial pathways

Description: L-glutathione is the bodys master antioxidant produced naturally by the body through the synthesis of 3 amino acids: L-cysteine, L-glutamate and glycine

This is one of the most common degradation pathways and one of the hardest to detect visually

Subsequently, Fe 2+ oxidizes the accumulated lipid peroxides to generate ROS, resulting in an excessive accumulation of ROS and thus facilitating the occurrence of ferroptosis (11)