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3.1 RONS 3.1.1 NMs Visualize RONS to Evaluate Macrophage Activity ROS are considered a series of chemically active substances generated from intracellular oxygen through electron transfer, primarily including hydrogen peroxide (H 2 O 2 ), hydroxyl radical (OH), hypochlorous acid (HOCl), and superoxide anion (O 2 ) [78]

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Acknowledgements This work was supported by grants from the National Natural Science Foundation of China (Nos

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Altogether, these observations suggest that the effect of ketosis on UPR activation is context and tissue dependent

Zhang, E., Yang, Y., Zhang, J., Ding, G., Chen, S., Peng, C., Lavin, M