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Considerations for elderly patients include: Assessing renal function to adjust medication dosing appropriately Evaluating the risk of bleeding due to comorbid conditions or concomitant medications Monitoring for potential drug interactions with other medications By focusing on each persons needs, we can better manage low platelet counts

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Variants at the HMIP-BCL11A-HBB loci account for 2050% of the variability of HbF levels and the relative contributions of these variants differ between ethnic groups [19], [20], [21], [22], [23]

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