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Some of these, including many neuropsychiatric drugs (e.g., SSRIs, SNRIs, amitriptyline & other TCAs, trazodone or nefazodone, gabapentinoids, (ar)modafinil, and Abilify), along with dihydropyridines (a subset of calcium channel blockers), fludrocortisone, midodrine, and cognitive behavioral therapy (CBT), all had over 20% of patients responding negatively

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D., Karelus, K., Felicio, L

While previous research has primarily focused on glomerular injury, recent studies have increasingly emphasized the role of renal tubular injury in the pathogenesis of DKD

Bioinformatics, 25(16), 20782079

Growing clinical evidence indicates that these complications pose substantial risks, with diabetic patients exhibiting a two-fold increase in pneumonia-associated mortality (Singh et al., 2020)