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StatPearls, Treasure Island (FL): StatPearls Publishing Copyright 2022, StatPearls Publishing LLC Sisson H (2015) Aspirating during the intramuscular injection procedure: a systematic literature review

While oral bioavailability may be lower compared to injections, it offers systemic benefits and convenience

This suggests that future studies should reduce heterogeneity-induced interference by clarifying strain characteristics, stratifying by disease stage, and standardizing detection protocols and experimental designs, thereby more accurately revealing the true association between Clostridium and ADs