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( a-b ) FT282 cells ( a ) or Ovcar8 cells ( b ) were treated with cisplatin (Cis) or Olaparib (Olap) alone or in combination with HAT inhibitor with or without KG, l-carnitine (l-carn), or O-acetyl-l-carnitine (Ac-Carn) supplementation

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236 Furthermore, glucose starvation leads to a suppressed lactate/pyruvate cycle, which inhibits neovascularization, hypoxia-induced vascular epidermal growth factor activation, and angiogenesis, and causes ultimate necrosis in tumor cells, especially for colon adenocarcinoma xenografts

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