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Particularly the intrinsic ability to exist in quiescent states has demonstrated efficacy in resistance to chemotherapy and radiotherapy

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For example, in lipopolysaccharide (LPS)-induced acute kidney injury, downregulation of HMGB1 and NCOA4 expression inhibits ferritinophagy, thereby alleviating ferroptosis in renal tubular cells (Tang et al., 2021)

Radiotherapy combined with nivolumab or temozolomide for newly diagnosed glioblastoma with unmethylated MGMT promoter: An international randomized phase III trial