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Based on the ICH S2 (R1) guidance document (International Council for Harmonisation, 2011) and White et al.(2020) relevant cytotoxicity was postulated at a minimum of 50% reduction in viability, as compared to the respective vehicle control

Isral, A

AAV serotype 2/1-mediated gene delivery of anti-inflammatory interleukin-10 enhances neurogenesis and cognitive function in APP+PS1 mice

However, the majority of research has predominantly focused on localized organ damage, with limited exploration of distant organ involvement

Upregulated microRNA-92b regulates the differentiation and proliferation of EpCAM-positive fetal liver cells by targeting C/EBP

Acknowledgements StarkAge Therapeutics is supported by the Deeptech Program from Banque Publique dInvestissement (France)