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conversely, telaglenastat treatment alone decreased cell growth by 45% and 80% at 96 h compared to that in the control (DMSO or DMSO+shGFP, respectively) (Fig

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Compound 968 can inhibit Rho GTPase-induced carcinogenic transformation by targeting glutaminase activity in some transformed and cancer cells with Rho GTPase/NF-B-dependent GLS activation (Wang et al., 2010