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BM-MSCs or BM-MSCs-exosome co-treatment caused anti-apoptotic impacts via a meaningful reduction in Bax/Bcl2 ratio and a rise in the expression of mitochondrial mitophagy genes, including Parkin RBR E3 Ubiquitin Protein Ligase ( Parkin ), phosphatase and tensin homolog (PTEN)-induced putative kinase 1 ( PINK1 ), unc-51 like autophagy activating kinase 1 ( ULK1 ), B-cell lymphoma 2/adenovirus E1B 19 kDa protein-interacting protein 3 ( BNIP3L ), autophagy related gene ( ATG5 ), ATG7 and ATG12

2013;1(4):e00089

Bryan is focused on helping biopharmas advance commercial effectiveness by providing access to complete data at any time through Veeva Compass, so biopharmas can gain comprehensive patient and HCP insights to help pave a path to treatment starts.

This review consolidates current evidence on the pharmacological activities, molecular targets, and therapeutic potential of ginsenosides in the management of depression