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Aqueous solvents such as sterile water or bacteriostatic water are preferred for in vivo rodent studies because they eliminate the confounding variable of DMSO's own biological activity, which includes membrane permeabilization and anti-inflammatory effects

10.3389/fcvm.2021.811670 83 LiuF.WangC.GaoY.LiX.TianF.ZhangY.et al (2018a)