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Among 17 members in humans and 16 members in mice, PARP1 alone is responsible for about 90% of all NAD + used by the PARP protein family [49]

Two inhibitors of cysteine proteases (cystatins 39,40 ) and two -2-macroglobulin homologues (I39) were also identified, as were three inhibitor of apoptosis proteins (I32), one of which is highly expressed in adults, where it may function to regulate one or more of the four schistosome caspases

Antioxidants (Basel) 13 (11), 1380

Hsia, H

The release of fluorogenic AMC from the substrate was measured by Infinite M200 fluorometer (Tecan, Mnnedorf, Switzerland) at 24 C in a 30 min kinetic cycle (2-min intervals)