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HIF1 regulates the differential gene expression in Gpr124 KO NPCs To obtain insight into the molecular mechanisms underlying the increased RG expansion in the absence of functional vessels in the cortex, we performed transcriptional profiling via RNASeq of freshly sorted VZ cells from Gpr124 KO or control embryos

Mayo-Smith MF

Note The author thanks James Batley for CDF data from the Solomon Islands

Cognitive enhancement effects persist for weeks after the peptide clears from circulation because dihexa initiates structural neuroplasticity changes that continue independently

Circadian Rhythm Studies The peptide is commonly examined in laboratory models involving biological timing systems and sleep-wake regulation pathways

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