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In line, cell numbers of MOLM-13 ABCC1 -knockout clones were massively reduced by exposure to AZD-4320 in concentrations that did not affect control cells (Fig

At a high level (Figure 3), soluble fibrinogen, typically as a 5 45 nm complex of three different polypeptides ( 2 2 2 ) (MW ~ 340 kDa) [81] plus internal fibrinopeptides A and B, and one of the most abundant proteins in plasma (present at typically 24 gL 1 [82,83]), is acted upon by the serine protease thrombin

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Rac1-NADPH oxidase-regulated generation of reactive oxygen species mediates glutamate-induced apoptosis in SH-SY5Y human neuroblastoma cells