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For the annual burden, we added the labor category for Chief Executives in response to comments on the CY 2026 OPPS/ASC proposed rule, and we now estimate a total of 415,296 hours for all hospitals (7,416 hospitals 56 hours) at a cost of $40,269,176.60 (7,416 hospitals [($128/hour 2 hours) + ($87.52/hour 40 hours) + ($97.30/hour 12 hours) + ($252.82/hour 2 hours]), to include the burden for the senior hospital official

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Adequate protein intake, biotin supplementation, and avoiding excessively rapid weight loss (more than 2-3 pounds per week) reduce the risk