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Genetic drivers of heterogeneity in type 2 diabetes pathophysiology

Mitochondria-targeted probes (e.g., MitoSOX) can track mitochondrial O 2 trends but are susceptible to photobleaching, redox cycling and DNA intercalation, so interpret only with HPLC verification, strict light management and matched membrane-potential conditions (Zhao et al

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PEYER'S PATCHES Specialized lymphoid follicles localized in the submucosa of the small intestine and appendix

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ATP7A facilitates the efflux of Cu+ from the intestinal epithelium into the circulation whereas ATP7B stores excess Cu+ in intracellular vesicles to maintain normal homeostasis (31)