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Description

These results demonstrate that DRD2 induces dimerization of PKM2 for Nrf2 binding and activation

Pediatrics 125 , e446-51 (2010)

The direct pathway involves activation of striatal dopamine 1 (D 1 ) dopamine receptors (which are coupled to adenylate cyclase) and stimulates the inhibitory -aminobutyric acid (GABA)/substance P efferents to the globus pallidus interna (GPi) and substantia nigra pars reticulata