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For severe overdoses (five or more times the intended dose), seek medical attention, as there is a risk of acute pancreatitis

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Within 5 to 8 days after the dose, the infants experienced significantly increased hemoglobin and reticulocyte counts, normoblastic erythropoiesis, improved mental status, regression of abnormal skin pigmentation, and reduction in tremors.[9] Three hundred sixty-six pregnant women in India received 50 mcg of oral vitamin B 12 or placebo capsules once daily beginning during their first trimester of pregnancy and continuing until 6 weeks postpartum

Source: Decreased Brain Levels of Vitamin B12 in Aging, Autism and Schizophrenia (2016) Remarkable improvements with B12 and folinic acid treatment