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Hepcidin has received more attention in recent years due to its ability to change intracellular iron content by regulating the expression of TF, TFR1, DMT1, and FPN1 (Vogt et al., 2021)

However, antioxidants and modulators of redox homeostasis could be modifiable risk factors in the onset and progression of allergies

Thus, converting the metabolic pathway of cancer cells from glycolysis to oxidative phosphorylation, coupled with exploiting the characteristic of elevated intracellular copper, may offer a promising new approach to cancer therapy

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This creates Reactive Oxygen Species (ROS) which generate more oxidative stress

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