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Oxidative stress in Caenorhabditis elegans : protective effects of the Omega class glutathione transferase (GSTO-1)

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Moreover, many tumors including PCa cells shed DNA into the serum or other easily accessible body fluids (e.g., semen, urine), simplifying the detection of GSTP1 epimutations in early tumorigenesis stages

Mechanistically, DUSP4-mediated phosphorylation of YTHDC1 at threonine residue T148 enhances its binding to SRSF3, thereby reducing nuclear retention of FTH1/FTL mRNA