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Mitochondrial dysfunction in intestinal epithelial cells impairs the ETC, reducing ATP production and inhibiting CBS and -lyase in the transsulfuration pathway, leading to a 3073.8% reduction in cysteine and GSH levels (RBC GSH: 1.78 0.28 mol/g vs

its activity could be stimulated by the GSH intracellular levels

Multiple linear regression analysis was performed to investigate the influencing factors for cognitive improvement in FES patients, by limiting the effects of confounding factors, such as age, education and baseline BMI

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Discussion APR-246 can restore the wild-type conformation of mutant p53 protein, therefore inducing apoptosis and inhibition of tumor growth in mice