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In a case series that examined 32 men who were diagnosed with CP/CPPS according to the NIDDK classification and who were refractory to behavioral and pharmacological therapies, 41% (13 of 32) had Hunner lesion on cystoscopy

& Cedar, H

& Alexiou, G

(5, 6, 7) Ibuprofen and other NSAIDs inhibit cyclooxygenase, an enzyme that produces inflammatory mediators, called prostanoids, from arachidonic acid