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Their results show that d- and g-tocotrienol inhibited NF-kB activity, cell growth, cell survival, and tumor growth in nude mice

Inflammatory IFIT3 renders chemotherapy resistance by regulating post-translational modification of VDAC2 in pancreatic cancer

The added advantage of these combinatorial approaches is that their tumor specificity may abrogate the systemic toxicity associated with single-agent by reducing dose requirements or may enable better therapeutic index in tumors compared to normal tissue

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Lipid peroxidation and ferroptosis in ER+ breast cancer cell lines is not dependent on ACSL4, but promoted by FAR1 and AGPAT3 We next investigated in more detail the potential molecular mechanisms of ferroptosis vulnerability induced by palbociclib in ER+ cell lines, by performing transcriptional and global proteomic profiling in MCF-7 cells treated with vehicle or palbociclib

Expression of a FRET-based ATP biosensor in the C