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Another in vitro study, however, found that the activated PTT was prolonged in proportion to the fall of factor XII and prekallikrein activity when POL was added to citrated serum

These help maintain optimal levels and prevent deficiency from developing

Andersen JK

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Tophi resemble granulomas and demonstrate leukocyte traffic, consistent with a role of inflammation in promoting tophus formation and remodeling

Mild stomach pain is the most common side effect, and it usually only happens at very high amounts that are higher than what is suggested