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Species specificity profiling of rat and human organic cation/carnitine transporter Slc22a5/SLC22A5 (Octn2/OCTN2) Drug Metab

Medical professionals should review its safety and effectiveness before recommending it

Biochem Biophys Res Commun 366(3):698704 Olleros Santos-Ruiz M, Sdaba MC, Martn-Estal I, Muoz U, Sebal Neira C, Castilla-Cortzar I (2017) The single IGF-1 partial deficiency is responsible for mitochondrial dysfunction and is restored by IGF-1 replacement therapy

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The ABCC1 protein features in resistance to taxane group drugs, and many studies have shown that overexpression of ABCC group proteins is a marker of resistance to drugs such as anthracyclines, vinca alkaloids, epipodophyllotoxins, cisplatin, etoposide, and epirubicin (Borst et al., 2000[7]