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Although NADPH is unable to translocate to the mitochondria across the inner membrane, its exchange between the cytosol and mitochondria is achieved by NADPH shuttle functions through the enzymes isocitrate dehydrogenase 1, [NADP +] (IDH1), and isocitrate dehydrogenase [NADP] mitochondrial (IDH2) (White et al

Inhibition of acetate and propionate assimilation by itaconate via propionyl-CoA carboxylase in isocitrate lyase-negative purple bacterium Rhodospirillum rubrum

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6 Previous studies proposed the role of reactive metabolites in methimazole-induced toxicity