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They can cause a wide range of muscle-related adverse events, including myalgia, myopathy and statin-induced rhabdomyolysis, known collectively as statin-associated musculoskeletal symptoms (SAMS)

Glutamate modulating medications were discontinued with clinician approval prior to enrollment and all other medications were kept constant (frequency/dosage) throughout the study

Abbreviations BMNPs: Biogenic Metallic Nanoparticles COSY: Correlation Spectroscopy CAM: Crassulacean Acid Metabolism HMBC: Heteronuclear Multiple Bond Correlation Spectroscopy HMQC: Heteronuclear Multiple Quantum Correlation Spectroscopy HRFABMS: High Resolution Fast Atom Bombardment Mass Spectroscopy HR-ES-IMS: High Resolution Electron Spray Ionization Mass Spectroscopy MWE/UPLC: MS/MS Microwave Extraction/ Ultra Performance Liquid Chromatography MTT: 3-(4,5- dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide NOESY: Nuclear Overhauser Effect Spectroscopy PO: Portulaca oleracea PUFA: Polyunsaturated fatty acids ROS: Reactive oxygen species TOCSY: Total Correlation Spectroscopy References Azuka OI, Ayalokunrin MB, Abu OL

[11] [13] Signs and symptoms [edit] Seborrhoeic dermatitis typically appears as oily, yellowish, flaky skin