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The clinical benefits were greatest in those who took folic acid for more than 12 weeks and those whose homocysteine levels dropped by more than 25%

The pathophysiology of depression remains incompletely understood, with antidepressants based on the monoamine hypothesis currently representing the most common treatment for depressive episodes

There are relatively few approaches for disentangling truly dysfunctional protein processing from whatever criteria the UPR uses to perceive ER stress, which are still not well understood

Factors affecting the development of cataracts include nutrition, oxidative stress, micronutrients and inflammatory factors, and also include genetics, toxicity, infrared exposure, hyperuricemia, and mechanical injuries

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This result is suggestive of the constitutive activation of LKB1/AMPK pathway in the livers of KO mice