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These oxidized fatty acids are also called oxylipins, and can be produced by vertebrates, fungi, or plants 58

The overproduction of tyrosinase contributes to hyperpigmentation one of the biggest skin concerns that people with more melanated skin often have (though hyperpigmentation can affect skin tones across the spectrum)

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Identifying these differences through advanced molecular and imaging techniques could help tailor ferroptosis-targeted interventions to specific subphenotypes, optimizing therapeutic efficacy

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