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Lipid peroxidation, a consequence of oxidative stress induced by radiation, entails the degradation of lipids when reactive oxygen species (ROS) generated by radiation interact with polyunsaturated fatty acids in the phospholipid membrane bilayer [49]

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Catalysis of GPx is essentially following three distinct redox modifications of the Se at the center of the active site, in a triad of selenocysteine, glutamine, and tryptophan, which reduces GSH to GSSG [14, 19]