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When used long-term, tesamorelin is primarily beneficial for reducing visceral fat but may require ongoing use to maintain results, as fat accumulation can return after discontinuation

FDA-approved peptides like semaglutide and tirzepatide may be covered when prescribed for approved indications (diabetes, obesity), but compounded peptides, off-label uses, and anti-aging applications are typically out-of-pocket expenses

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The lipolytic mechanism of AOD-9604 is directly inhibited by insulin