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Jong YJ provided care for 12 patients with muscular laminopathy from 5 families affected by CMD, EDMD2 and EDMD

This mitochondrial failure results in the immune senescence of those same T cells and a systemic accelerated aging phenotype, marked by motor deficits, cardiovascular dysfunction, and cognitive decline (Desdn-Mic et al., 2020)

78 Thus, the impact of astrocytic lactylation is defined by its specific downstream molecular targets rather than a generalized inflammatory response (Table 2)

An SMN-dependent U12 splicing event essential for motor circuit function

Using a similar strategy, Bmx-CreERT2 - controlled GFP expression at E14.5 decorates mesenteric arteries at 24 h after 4-OHT administration (Supplementary Fig

The association between vitamin D and gut microbiota: A systematic review of human studies