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In contrast, substitution to an amidated proline instead of an amidated tyrosine in the C-terminus of rAmy is well tolerated, resulting in enhanced affinity and activity at both the CTR and AMYRs, but, in some cases, reduced selectivity between these receptors 18

Even levels in the upper-normal range do not guarantee sufficiency

Plant MOLECULAR Defence Mechanism 3.3.1

In mammals, this generally corresponds to PTCs located more than 5055 nucleotides upstream of the final exonexon junction [1, 47]

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They also indicated that PEG coating leads to a decrease in cellular uptake of gold NPs, suggesting that stable surface coatings of the NPs disrupt the interface between the metal NP and oxygen-based molecules in the environment by scavenging ROS via chemical interactions with alcohols and thiols on the surface of the NPs [113]