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Approximately one third of patients with schizophrenia are considered to be treatment resistant [5], with the majority of these (2334%) failing to respond appreciably to dopamine-blocking antipsychotic medications from their first episode of psychosis (FEP) [6, 7]

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(2004) Given the paired nature of the crossover design and the non-normal distribution of some variables, within-subject comparisons across treatment periods were performed using paired Wilcoxon Signed-Rank tests, with p-values adjusted for multiple comparisons using the BonferroniHolm method

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Compared with EEG, fNIRS is more powerful against motor artifacts and therefore, more suitable to study the neuronal mechanisms in real motor behavior (Seidel-Marzi and Ragert, 2020)