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Lilly redesignated the compound as LY3502970 and later assigned the international nonproprietary name orforglipron

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Even at recommended storage temperatures (2-8C refrigerated, or up to 30C for in-use pens), semaglutide loses approximately 1-2% potency per month if exposed to fluctuating conditions

For tirzepatide, every 10C increase in temperature roughly doubles the degradation rate

For the purposes of this article, we focus on the Roux-en-Y because the recommendations related to that surgery specifically call for vitamin B-12 and also have recommendations on how it should be taken