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In addition, thyroid hormones and thyroid status have varied effects on the pharmacokinetics and actions of other drugs

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A number of studies have also demonstrated that abnormal activation of -adrenergic receptors (-ARs), which mediate the effect of stress, might contribute to A peptides production resulting in accelerating amyloid plaque formation in vitro and in vivo by enhancing -secretase activity (Ni et al., 2006) and that blocking -ARs attenuates acute stress-induced A peptide production (Yu et al., 2010)

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