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In addition, the alteration of GAPDH and PK in AD was further described by an immunoproteomic approach that demonstrated the presence in the CSF of autoantibodies against these enzymes (397), consistent with the notion that proteins undergoing ox-PTMs become toxic to neurons, which induce clearance systems and immune responses

If you have allergies, you should advise your medical professional before receiving treatment

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In other ASD models, such as 15q dup mice [34], Oprm1 -KO mice [42], Oxtr -KO mice [33], and C58/J mice [38], oxytocin selectively improved social deficits, without influencing other ASD symptoms

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During early growth (until about the second year after birth), about 1020% of the amino acid pool is used in growth and is thus not available for GSH synthesis and one-carbon metabolism [7577]