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This study suggested that SLC7A11 may be a clinically viable target for both therapeutic potential and safety

Adding in the 13 yellow genes with less-robust evidence of CVS association (Tables 2, 5), and 71/80 (89%) of participants presented with at least one Qualifying variant

If this phenomenon is prevalent in cells, it would lead to mis-incorporation of amino acids generating defective proteins that might affect cellular viability [21]

Combining Gsto2 smFISH with PENK immunofluorescence (Fig

The FDA did not cite any issues with Ultomiris efficacy or safety data from the Phase III CHAMPION-NMOSD trial

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