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A combination of low selenium and genetics may play a role in the susceptibility to Keshan disease as individuals carrying the Leu198 variant of GPX1 , which is associated with lower expression, especially in the context of lower selenium levels, are at greater risk of developing Keshan disease [36]

The details of such reactions are extensively reviewed in previous publications [77, 79]

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Lichty, J

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Weeks 1 to 4 (introductory phase) use a 1 to 2 percent concentration once daily in the evening, which lets the skin acclimate while the physician assesses tolerance