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Oxidative Stress and Autophagy Mediate Anti-Cancer Properties of Cannabis Derivatives in Human Oral Cancer Cells

Concurrent treatment with naringin at different doses (i.e., 50, 100, and 200 mg/kg, p.o.) resulted in a significant decrease in immobility time, hyperalgesia, oxidative stress, and serum TNF- levels, in a dose dependent manner

Parkin also ubiquitinates the mitochondrial fusion protein Mitofusin 1 and 2 (mfn1/2), thereby promoting the repair of damaged mitochondria by regulating mitochondrial dynamics [80]