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The studies tested various doses including 0.25 mg, 0.5 mg, and 1 mg daily via subcutaneous administration over periods ranging from single doses to 24 weeks of continuous therapy

Among the PRMT family, PRMT1 stands out due to its broad substrate specificity and abundance in various cell types, including renal cells [11, 13]

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& Yi, C

The researchers administered glutathione-MDI conjugates to mice and found that MDI is transferred to a particular lysine residue in albumin, probably via a transcarbamoylation reaction