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Please speak with your primary physician if you take blood thinners to make sure that you can safely stop taking these medications

Rectal administration provides localized delivery of biologics, directly targeting intestinal inflammation

in preclinical models it activates the VEGFR2-Akt-eNOS signaling axis to promote angiogenesis and tissue vascularization ( It also engages ERK1/2 and FAK-paxillin pathways that regulate endothelial cell migration and fibroblast activity, and upregulates heat shock proteins (HSP70/90) for cytoprotective effects in gastrointestinal tissue models ( Research across multiple rodent injury models has characterized its activity in tendon, muscle, nerve, and GI tissue contexts

Learn more: How often to get MIC B12 injections The FDA does not approve compounded medications for safety, quality, or manufacturing

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If youve got the necessary bank account to pay for it and can overcome the scary idea of injections or other procedures on your genitals, you could try it, but there are very serious potential risks and little published data to support doing something rather extreme like this