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Supplementary material The Supplementary Material for this article can be found online at: References 1 AbdelmegeedE.ShaabanM

Oxidative stress has been identified as a potential factor in the pathogenesis of vitiligo

These in vivo results align with the in vitro data, consolidating the understanding that GHK-Cu exerts its protective effects in ALI by inhibiting excessive inflammatory responses through its anti-inflammatory and antioxidant properties, mediated by the suppression of NF-B and p38 MAPK signaling pathways [1]

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GPX1 is an important enzyme that plays a key role in protecting cells from oxidative stress by catalyzing the reduction of hydrogen peroxide and lipid hydroperoxides