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Description

Release of O 2 - occurs towards the cytosolic side of the inner mitochondrial membrane

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It has been demonstrated that 80% of all bacterial infections in humans are associated with biofilm (Costerton et al

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10.1074/jbc.M111.248310 69 GroerC

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In mammalian cells, mtDNA is a double-stranded circular genome ranging from 16.2 kb in mice to 16.7 kb in pigs [10, 11]

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While oxidative stress typically enforces the pro-tumor N2 phenotype, targeted ROS generation has been shown to repolarize TANs toward the anti-tumor N1 state, restoring their ability to kill cancer cells and recruit T cells [211, 212]

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