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Laboratory studies using 5-amino-1MQ in aged animal models have revealed that NNMT inhibition modulates many age-associated metabolic parameters, including alterations in muscle tissue metabolism and cellular stress response pathways

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In the first protocol, growth factor-reduced matrigel was pipetted into prechilled 24-well plates (150 mL matrigel per well) and polymerized for 45 minutes at 37C

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