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Consult a healthcare provider if you experience persistent side effects

Several studies have evaluated SAMe for a type of cholestasis called intrahepatic cholestasis of pregnancy (ICP)

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Jiajun Sang, Chengxia Kan, Qiming Fan, Sufang Sheng, Xiaodong Sun, Kexin Zhang, Ferroptosis regulator families in metabolic diseases: Molecular networks and therapeutic opportunities, Journal of Trace Elements in Medicine and Biology, 10.1016/j.jtemb.2026.127895, 95 , (127895), (2026)